<p>I've done several flights and long drives after running ultras. No problems. </p>
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<p>I second Buzzie's suggestion for compression socks/calf sleeves. My feet swell when flying and the compression helps a lot. I wear them every time I fly now even if I'm not running. I think most drug stores sell cheap compression socks for diabetics if you want something just for the flight.</p>
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<p>I'll add that your immune system will be compromised after running. You might want to take an immune booster before your flight to help prevent any colds/flus. I got a cold once coming back from Las Vegas Marathon. Wow, that sucked (the cold and the marathon). </p>
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<p>ChrisG</p>
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<p>I second Buzzie's suggestion for compression socks/calf sleeves. My feet swell when flying and the compression helps a lot. I wear them every time I fly now even if I'm not running. I think most drug stores sell cheap compression socks for diabetics if you want something just for the flight.</p>
<p> </p>
<p>I'll add that your immune system will be compromised after running. You might want to take an immune booster before your flight to help prevent any colds/flus. I got a cold once coming back from Las Vegas Marathon. Wow, that sucked (the cold and the marathon). </p>
<p> </p>
<p>ChrisG</p>